Today’s Solutions: January 30, 2023

From helping the body fight cancer to reducing heart disease and improving memory, the health benefits of exercising regularly have been well-documented. What has been less clear are the intricate mechanisms behind working out and good health.

Aiming to fill this gap, a recent study shines new light on high-intensity workouts specifically, finding that they can have incredible effects on the metabolites circulating through the body and, as a result, lead to improvements in a wide range of bodily functions.

“Much is known about the effects of exercise on cardiac, vascular and inflammatory systems of the body, but our study provides a comprehensive look at the metabolic impact of exercise by linking specific metabolic pathways to exercise response variables and long-term health outcomes,” says senior author Gregory Lewis.

“What was striking to us was the effects a brief bout of exercise can have on the circulating levels of metabolites that govern such key bodily functions as insulin resistance, oxidative stress, vascular reactivity, inflammation, and longevity.”

To arrive at this conclusion, Lewis and his team drew on data from a heart study concerning 411 middle-aged men and women. The team measured the levels of 588 circulating metabolites before and immediately after 12 minutes of vigorous exercise. They found favorable changes in a number of metabolites.

For example, glutamate, a key metabolite linked to heart disease, diabetes, and decreased longevity, decreased by 29 percent. And DMGV, a metabolite associated with increased risk of diabetes and liver disease, dropped by 18 percent.

“We’re starting to better understand the molecular underpinnings of how exercise affects the body and use that knowledge to understand the metabolic architecture around exercise response patterns,” says co-first author Ravi Shah. “This approach has the potential to target people who have high blood pressure or many other metabolic risk factors in response to exercise, and set them on a healthier trajectory early in their lives.”

Solutions News Source Print this article
More of Today's Solutions

Avatar’s motion AI tech helps researchers detect rare diseases

Researchers are using motion capture artificial intelligence technology that brings characters to life in films like Avatar to track the onset of diseases that ...

Read More

The top 9 mistakes people make when trying to establish a healthy routine

If you can’t figure out why you struggle to maintain a healthy routine, no worries. We have a story from Groom+Style that lists the ...

Read More

World’s largest wealth fund drops fossil fuel investments

The world’s biggest wealth fund was built on Norway’s oil and gas production revenue. Now, the fund is shifting course and taking a stand ...

Read More

Listen to this fascinating piece of ambient music composed by stars

Though we can’t hear them, stars propagate some incredibly soothing soundscapes through the vacuum of space. And for the first time, music composed from ...

Read More